منابع مشابه
Distinct autoimmune syndromes in morphea: a review of 245 adult and pediatric cases.
OBJECTIVE To determine the prevalence of extracutaneous manifestations and autoimmunity in adult and pediatric patients with morphea. DESIGN A retrospective review of 245 patients with morphea. SETTING University of Texas Southwestern Medical Center-affiliated institutions. Patients Patients with clinical findings consistent with morphea. MAIN OUTCOME MEASURES Prevalence of concomitant au...
متن کاملAutoimmune polyendocrine syndromes.
N Engl J Med 2004;350:2068-79. Copyright © 2004 Massachusetts Medical Society. he autoimmune polyendocrine syndromes are diverse, and their diversity is a characteristic that is both clinically important and instructive when their basic immunologic features are considered (Table 1). 1-4 These syndromes include monogenic disorders (such as autoimmune polyendocrine syndrome type I, which has clas...
متن کاملPolyglandular Autoimmune Syndromes (pga)
Definition of PGA PGA involve multiple endocrine gland insufficiencies (minimum two), being frequently associated with diseases of non-endocrine organs, and occur in individual patients and their families.1,2 The autoimmune endocrine associations recognise more generics: autoimmune polyglandular syndromes (APS), autoimmune polyendocrine disease (APD), polyglandular failure syndromes (PFS), and ...
متن کامل[Vitiligo and morphea: autoimmune cutaneous side effects of interferon treatment].
The interferons comprise a family of proteins belonging to the cytokines involved in regulation of the immune response. They exert antiviral, antineoplastic, antiangiogenic, and immunomodulating effects. High-dose interferon alfa is the only treatment to date that has been shown to improve disease-free survival in patients with advanced melanoma in randomized prospective trials. Its side effect...
متن کاملVitiligo and Morphea: Autoimmune Cutaneous Side Effects of Interferon Treatment
The interferons comprise a family of proteins belonging to the cytokines involved in regulation of the immune response. They exert antiviral, antineoplastic, antiangiogenic, and immunomodulating effects. High-dose interferon alfa is the only treatment to date that has been shown to improve disease-free survival in patients with advanced melanoma in randomized prospective trials. Its side effect...
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ژورنال
عنوان ژورنال: Archives of Dermatology
سال: 2009
ISSN: 0003-987X
DOI: 10.1001/archdermatol.2009.79